Hypoxic pulmonary vasconstriction

Description

Hypoxic pulmonary vasoconstriction (HPV) is a reflex contraction of vascular smooth muscle in the pulmonary circulation in response to a low regional partial pressure of oxygen. It is important mechanism for matching of regional perfusion and ventilation in the lung. HPV can decrease the blood flow to the nonventilated lung. HPV is widely conserved, hemostatic, vasomotor response of resistance pulmonary arteries to alveolar hypoxia. This video explains in detail about introduction, background physiology, mechanism, factors affecting and clinical implications of HPV.