Organ protection during cardiopulmonary bypass

Description

Modern cardiac surgery, heralded by the advent of cardiopulmonary bypass (CPB) more than 5 decades ago, continues to be challenged by the risk of organ dysfunction and the morbidity and mortality that accompanies it. Catastrophic organ system failure was common in the early days of CPB, but advances in perfusion, anesthesia, and surgical techniques have allowed most patients to undergo surgery without major morbidity or mortality. However, organ dysfunction ranging in severity from the most subtle to the most severe still occurs, manifesting most frequently in patients with decreased functional reserves or extensive comorbidities.This presentation deals with organ protection during cardiopulmonary bypass.